A new approach
to industrial
innovation

We invest in fundamental scientific breakthroughs by leading innovators to solve industry’s hardest problems in critical sectors

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ENERGY MATERIALS MANUFACTURING AGRICULTURE

We invest in companies with massive potential

We work with our portfolio founders to chart the path from scientific breakthrough to commercial success: accelerate technology de-risking, verify product market fit, and reduce time/resources to market. Scaled successfully, these companies will enable us to redefine industries across the globe while meeting critical climate goals and feed a growing world sustainably.

OUR FOCUS

ISV identifies, invests in and builds breakout companies driving industrial innovation

ENERGY

Generation, Transmission, Storage, Efficiency

MATERIALS

Mining, Metal Refining, Chemicals

MANUFACTURING

Built Environment, Infrastructure, Bio

AGRICULTURE

Crop Resilience and Growth, Processing, Soil, Water

What We Look For

As an early-stage investor, we seek leading innovators commercializing scientific breakthroughs to disrupt trillion-dollar markets. We invest in multi-disciplinary teams driving cost-efficient production, supply chain resilience, and the shift to cleaner, cheaper energy and materials to redefine industries.

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PORTFOLIO COMPANIES

Zero-carbon, low-cost, long-duration, grid-scale energy storage and industrial heat

Carbon-negative Portland cement

Direct discovery of microbial ensembles with advanced microbial interaction screening technology

Reimagining battery manufacturing from the inside out

Bespoken bacteria for biomanufacturing using high throughput functional genomics and machine learning

Advanced resins for industrial additive manufacturing

Advanced materials solution for better Li-metal batteries

Transforming the food system using seaweeds — the most sustainable protein source on the planet

Biocatalysis for engineered enzymes to transform chemical engineering

Next-gen geothermal technology for 24x7 carbon free energy

Planet-friendly heating and cooling using heat pumps

Quantum entanglement solutions for next-gen telecom networks

Wireless charging to power the future of mobility

Localized metal manufacturing for a greener planet

Industrial photosynthesis to transform CO2 into everyday products

Electrolysis tech driving chemical manufacturing electrification and decarbonization

OUR TEAM

Alain Harrus

Investment Team Managing Partner, Co-Founder

Robert Ethier

Investment Team Managing Partner, Co-Founder

Tom Boussie

Investment Team Managing Partner

Alita Carbone

Investment Team Principal

Matt Price

Portfolio Support Team Venture Partner

James Burke

Portfolio Support Team Government Relations

Frieden McLean

Portfolio Support Team Dual Use Technology Lead

Advisors

With deep connections to an expansive network of high-tech focused visionary leaders across academia, corporations and venture ecosystems who are committed to supporting scientific entrepreneurs and innovations, we partner with our advisors to source, diligence, mentor and connect ISV portfolio companies with the resources needed for their future success.

Ilan Gur

CEO, ARIA, Co-founder, Activate

Vinit Nijhawan

MD, Mass- Ventures, Serial entrepreneur

Daniela Fernandez

Founder, Sustainable Ocean Alliance

Sam Sabin

Board Member, Sustainability Lead

Annette Finsterbusch

Founder, Applied Ventures CEO

Andrew Chang

Managing Director, Activate

Marc Tarpenning

Co-founder

Hannah Murnen

CTO, Former MD at Activate

Jeff Dunbar

Senior Sustainability Director - Innovation, CBRE

Tom McDonald

CSO Orbital Materials, Co-Founder & CEO Mosaic Materials

RECENT NEWS

Latest news about our portfolio companies

Twelve Secures $83 million in Additional Series C & Project Funding

Feburary 18, 2025
ACT Expands Charging Portfolio with Next-Generation Wireless Power Technology

February 10, 2025
Resonant Link Medical Launches to Power Better Health for All

January 29, 2025
Schneider Electric and Liminal Partner to Enable High-Quality, Scalable EV Battery Production While Minimizing Waste

January 23, 2025
Industrial Breakthrough: Brimstone to Produce Alumina, Bolstering U.S. Aluminum Supply Chain

January 8, 2025
Fervo Energy Secures Additional $255 Million Funding to Meet Unprecedented Energy Demand

December 19, 2024
Umaro and Sway Receive $1.5M Dept. of Energy Grant to Turn Seaweed Waste into Sustainable Bioplastics

November 25, 2024
Concerto Biosciences Doses First Participant in Phase 1 Trial of ENS-002, a Microbiome-Based Therapy for Atopic Dermatitis

November 20, 2024
Biotech Firm Revolutionizing Amino-Acid Manufacturing Closes $12 Million Series A Financing Round

October 29, 2024
SUN METALON and Komatsu Launch Joint Research on Innovative Recycling Process for Iron-based Polishing Sludge

October 22, 2024
Liminal Secures Strategic Investment from LG Technology Ventures To Expand and Accelerate Commercial Deployments

October 15, 2024
Gradient’s All-Weather 120V Window Heat Pump Is ENERGY STAR Certified!

October 11, 2024
polySpectra launches its new 3D printing resin for home and small business use

October 10, 2024
Whole Foods Identifies Plant-Based Aquatic Ingredients as a Major Growth Trend for 2025

October 7, 2024
Sepion Technologies Secures $17.5 Million to Build Advanced Battery Separator Manufacturing Facility

October 3, 2024
Sumitomo Corporation Global Metals Co., Ltd. and SUN METALON. Inc. Announce Investment and Business Alliance to Lead Metal Industry Decarbonization

October 3, 2024
SUN METALON Secures $21 Million in Series A Funding to Lead Metal Industry Decarbonization

October 2, 2024
Gradient Selected Grand Prize Winner of the 2024 CEE Integrated Home Competition

October 1, 2024
Twelve Announces $645 Million in Funding Led by TPG to Transform CO2 into Jet Fuel and Electrochemicals at Scale

September 19, 2024
X-Caliber Rural Capital Affiliate Closes $100MM Loan for World’s Largest Next Generation Geothermal Energy Project

September 10, 2024
Test of a prototype quantum internet runs under New York City for half a month

August 24, 2024
Concerto Biosciences Receives FDA Investigational New Drug Clearance for Live Biotherapeutic Product to Treat Atopic Dermatitis

June 26, 2024
Antora Energy Selected by ARPA-E for $14.5 Million Award to Accelerate Launch of Heat & Power Product

June 25, 2024
Aepnus Technology raises $8M in seed financing

June 17, 2024
Sepion Advances EV Battery Safety with AI-Driven Non-Flammable Electrolyte

April 30, 2024
Industrial Demonstrations Program Selects Brimstone for Transformational $189 Million Federal Investment to Decarbonize Cement Industry

March 22, 2024
Umaro Foods Secures $3.8 Million in Financing, Launches Retail Expansion at Expo West

March 7, 2024
Antora Energy Raises $150 Million to Slash Industrial Emissions and Spur U.S. Manufacturing

February 22, 2024

Current JOBS

Join companies with massive impact potential

Making cement carbon-negative without changing the product or price

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Powering the Future of Electric Mobility

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Building a food system that supports a wild and thriving planet

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Electrifying heavy industry with zero-carbon heat and power

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Transforming battery manufacturing from the inside out

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Domestication of bacteria

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Production of advanced materials, turning 3D printing into a production tool

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Reinventing humanity's relationship with microbes

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Cody Finke

CEO and Co-Founder

Impact science ventures has the superpower of being able to think critically with you about the unique fundraising strategies required for hardtech. ISV puts the company first. if you are a hardtech entrepreneur, these are the type of investors that you want to work with.

Etosha Cave

CSO & Co-Founder

Impact Science Ventures is building for the future. They have a talented team of industry veterans who can provide financial resources and knowledge for deep tech entrepreneurs.

Matt Price

President & CFO

The experience of the ISV team and their alignment with Activate's missions provides ISV with a unique position of building strong and valuable relationships with all Activate Fellows during the earliest stages of their companies. Their deep understanding of what it takes for hard tech entrepreneurs to create equity value in their business causes them to be a go-to investor for Activate companies.

Andrew Ponec

CEO & Co-Founder

The folks at ISV are always one of my first calls when we're discussing big strategic decisions. Their depth and breadth of experience, alignment with our vision, and willingness to go to bat for our team make them an incredibly valuable partner.